What it is
L-Arginine is an amino acid the body makes and also takes in from protein foods. It is called conditionally essential because in times of stress or illness the body may not make enough.
What it does in Memoclear
Arginine is the raw material for nitric oxide, or NO. An enzyme in the lining of blood vessels converts arginine into NO, and NO tells the muscle around the vessel to relax. A relaxed vessel is a wider vessel, which means more blood, oxygen and nutrients get through. In Memoclear the plain base form is there to start that process quickly after the capsule dissolves.
Where it comes from in food
Found in chicken, turkey, pork loin, pumpkin seeds, peanuts, soybeans and dairy.
What the research says
Arginine's role in nitric oxide production is textbook biochemistry and not in doubt. Studies on arginine supplements for blood pressure and blood-vessel function show modest effects, and the gut and liver break down a large share of oral arginine before it reaches the blood, which is why the formula also includes citrulline. Direct trials of arginine on memory in healthy adults are few.
Who should be careful
Arginine relaxes blood vessels, so if you take blood pressure medicine, nitrates or erectile dysfunction medicine, ask your doctor first. People who have had a recent heart attack should not take arginine supplements without medical advice. Arginine can also trigger outbreaks in people who get frequent cold sores, and high doses can upset the stomach.
Where it sits in the formula
L-Arginine (base) works alongside the other five ingredients: L-Arginine AKG 2:1 Extract, L-Citrulline HCL, L-Citrulline Malate, Niacin (Vitamin B3), Beta-Alanine. Together they cover blood flow, cell energy and neuron protection in one daily capsule.
Further reading
L-Arginine, nitric oxide and cerebral blood flow, PubMed. This research is on the ingredient, not on the finished Memoclear product.